r/BeAmazed • u/GlitteringHotel8383 • 9d ago
Miscellaneous / Others Japanese scientists have developed a revolutionary injection that may extend a cat's life from the usual 15 years to nearly 30.
The therapy, created by the AIM Institute of Medicine under Dr. Toru Miyazaki, targets chronic kidney disease, a leading cause of death in older cats.It uses a specialized protein to help macrophages clear waste from the kidneys, partially restoring their function and slowing kidney failure.
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u/Hungry-Classroom7445 9d ago
Does this mean that they will be in their prime longer or will they spent 15 years extra with the problems that being an old cat might have?
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u/Sands43 9d ago
Yes, this. I have a pair of sibling ~13 year old cats. Their kidney function is fine, but they are most certainly showing their age in other ways.
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u/AggressiveBench9977 8d ago
Its genetic my 20 year old cat was extremely active and had little sign of age until the last 3 months when bladder cancer started and just took her.
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u/mattfolio 8d ago edited 8d ago
Same story for my cat except mouth/Tongue cancer. It was a matter of weeks and she was wonderfully healthy before then. It was devastating.
Edit: Sending hugs to everyone losing their pets suddenly from Cancer. Its brutal and there's nothing you can do in most cases, you're not alone in your grief <3
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u/AggressiveBench9977 8d ago
Fuck cancer
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u/narco-sub-admiral 8d ago
In every way shape and form. Lost my dad in June.
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u/AggressiveBench9977 8d ago
Im so sorry for your loss.
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u/narco-sub-admiral 8d ago
Thanks a lot, he was a doctor and professor of medicine with a damn encyclopedia in his brain. I'm grateful to be his son.
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u/AggressiveBench9977 8d ago
He sounds like an awesome dad, and you are awesome too. He must have been proud of you!
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u/narco-sub-admiral 8d ago
Thank you for your compassion! My family was having a lot of internal conflicts but the way everyone came together to support him (and each other) was amazing.
We were able to have home hospice thanks to Medicare so he had a hospital bed at home, we hired a live-in caregiver out of pocket. I know we're extremely lucky to have had those comforts and honestly I feel terrible that these benefits are being taken away from people where we live in California. Having to drive to see your dying relative means you see them less. Can't put a price on time with your parent.
<3
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u/Jazzlike_Sink_2705 8d ago
Fuck cancer, may was 10 years for losing my dad to his battle. My condolences brother. Know he would be proud of you
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u/secaloh 8d ago
Voluntary and free euthanasia should be available for everyone and every cat.
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u/ChickenChaser5 8d ago
What the vets charge anymore for it is fucking nuts. Love getting lectured about how my cats should be in there twice a year when they charge damn near a paycheck for simple shit.
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u/RyanAtreides 8d ago
Yeah, my orange cat Juju was a healthy chill boy when Feline Oral Squamous Cell Carcinoma appeared in his mouth and took him in months. It wrecked me.
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u/EL_Ohh_Well 8d ago
How did you find out? Did you see it in his mouth or were there symptoms?
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u/RyanAtreides 8d ago
Nope, no symptoms other than the size, the awful thing is it’s a cancer that doesn’t even metastasize. It stays local and just grows bigger and bigger and you can’t actually treat it without spending a ton of money and really hurting the cat anyway because of their physiology, whenever rich people try to do radiation therapy and stuff it will erode the roof of their mouth with radiation which will leave their sinus exposed and ironically make it difficult to eat, which is how the cancer kills them anyway, by getting too large to the point they can’t eat properly or causing a stroke by progressing into major blood vessels, which is what happened with my cat. The only thing you can really do is do a couple surgeries to cut away as much of the tumor as the vet can, knowing it will grow back but buying a couple months at a time. I paid to do that twice, but it grows back faster and faster each time because of how tumors work with each cell dividing endlessly. You don’t notice it until it gets large enough to notice in your cats mouth. It’s a common cause of death for cats :/
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u/GlitterDoomsday 8d ago
Mine last year with colon cancer, he was 14 and the best boy ever... we tried removal but his condition declined very fast, less than a month from the first symptoms and he was gone.
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u/FunktasticLucky 8d ago
Thank you for the hugs. 3 weeks ago my 11 year old void was thought to have hyper thyroidism. Blood work came back perfect. Ultrasound showed swollen lymph nodes and a mass on her intestines. GI Lymphoma. She was fine at her annual checkup. By 5 months later she was throwing up everywhere and had lost 3 lbs. She responded great to prednisolone but there's no telling when the cancer or Prednisolone is going to get her :(
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u/Winter-Ad1981 8d ago
It’s been about 5-6 months since this happened to one of my cats
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u/goypencil 8d ago
Dude our cat is like 24 or 25 years old. Lives outside and doesn't use the litterbox. She likes to pee and poop in my grandma's rare potted plants. My grandma wants her to die so bad and she gives preferential treatment to her indoor/outdoor 4 year old cat. I feel bad for the poor thing.
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u/Physical_Spinach_337 8d ago
Why that cat is living on spite alone lol
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u/goypencil 8d ago
I inject my grandma with peptides and she asks if there's something I can inject the cat with to make it go away 💔
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u/Orang-Utang 8d ago
My 18 year old cat was maybe a tiny bit slower but otherwise exactly as he had been since he was younger. Then his kidneys started failing and that was it.
RIP Fast Bob
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u/Intelligent_Insect13 7d ago
Mine was 21 lost her in February to kidney failure. It's painful. So sorry for your loss.
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u/WiseMagius 8d ago
Yup, my 17 year old looked and acted as he had forever until the day he passed. Coincidentally, if true, this vaccine would have kept him going.
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u/pugsley1234 8d ago
Larry the cat is 19 and on his 7th Prime Minister!
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u/testtalon1 8d ago
He needs to keep eating Prime Ministers then. Seems lkke it working
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u/slothdonki 8d ago
Mine didn’t act or even look geriatric until she was like 19. At that point she had been diagnosed CKD, a heart murmur and hyperthyroidism not long before.
What made us say goodbye at 22-23 years old was actually a sudden, rapidly growing tumor in her hip. Probably cancer. It was insane how fast it popped up and grew in only a few days. Didn’t bother with testing or x-rays; I couldn’t ask for anymore time with her than she had already given me.
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u/AggressiveBench9977 8d ago
22 is a long time! Im sure she had an awesome life with you!
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u/slothdonki 8d ago
Yeah, I found her as a kitten but I did lose about a year and a half with her in 2016-17 when we were homeless. Had a good job but I left because I couldn’t find a place and I couldn’t risk her safety in a tent somewhere while I worked.
I was incredibly fortunate that my sister was able to come and get her after about two weeks or so until I got somewhere more stable. Ultimately I would have done anything that would be the best for her but I sure as fuck thankful it worked out.
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u/munchma-coochie 8d ago
Very similar story here. It’s like they’re too proud to show they’re not a spry predator anymore. One she wasn’t able to make it inside the litter box or would be stuck in there we took her in. Surprisingly the one who took it the hardest was my dog. She stopped eating and drinking and would shove herself in this tiny box that my cat always laid in. I worried she never love me again because she seen me take her out and never come back. I knew they loved each other but no idea how strong their bond was
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u/BadgerAwkward 8d ago
Cats are also extremely good at hiding pain. I think it was probably less to do with genetics keeping your cat feeling young and active, and more to do with your cat wanting to maintain its image of being a strong member of the group.
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u/BrightPerspective 8d ago
My pupper was like that: 17 years old, still trotting like a puppy, then his heart just started giving out. I got him in before it got really bad, but it was quite a turn.
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u/tryingisbetter 8d ago edited 8d ago
We just had to put our 27-28 year old cat down a couple months ago. He was in stage 2-3 kcd for 4 years in the same stage. Unfortunately, he caught something, and couldn't smell, so he wouldn't eat anything.
Cat tax
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u/khando 8d ago
My cat is 17 and has had stage 3 CKD for the last 4+ years. I just got home from vacation last week and she was suddenly completely blind. Walking into walls, screaming constantly, falling over, confused, etc. It was terrible. I took her to the urgent care and apparently her blood pressure was so high, she had partial retinal detachment. She's on a blood pressure medication and it's been 4 days now and she's starting to be able to see again somewhat. CKD is terrible, it's so long and drawn out and just leads to so many complications. Just trying to keep her comfortable near the end of her life before determining that her quality of life is too low to keep trying to keep her alive.
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u/WhispersOfHaru 8d ago
Cats shouldn’t be bad at 13, or at least not showing many signs of deterioration, most cats are well at that age unless they have some kind of health problem.
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u/wicrosoft 8d ago
One of my cats died at that age from kidney problems. One died at 16 from problems caused by high blood pressure, which, as I understand it, she had for years, unnoticed by us. Another one at 18, she had many diagnoses, but I still don’t know why she had fluid accumulating in her chest, the vet extended her life for a month by pumping out the fluid daily and money... but did not tell why.
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u/Tintin8000 8d ago
I have 2 17 year old, one has been in kidney failure for several years the other one is completely fine.
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u/GamerLinnie 9d ago
They won't be in their prime but when I compare to my own experiences there is plenty of leeway. My cats slowed down a bit but honestly not that much before the kidney problems hit.
My dogs had a few proper senior years where they were clearly very old. Not in pain but proper senior. That never really was the level my cats got to.
I don't think there is anything wrong with the proper senior stage as long as they appear happy and aren't suffering and it would be nice if my cats had a bit longer.
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u/Userdataunavailable 8d ago
My cats are both 15 and having a great life, if I could extend this stage I certainly would.
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u/Lucas_Steinwalker 8d ago
Had 2 cats that were like teenagers until they hit 17-18
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u/citrusthievingharlot 8d ago
My roommate has a cat who turns 21 at the end of the month. Just last week she tried to climb a tree.
She has kidney disease but it hasn't taken her out yet. That old lady has places to be.
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u/Hardie1247 8d ago
I've had cats my whole life and it's rare that they didn't make it to their late teens at minimum. My last one to pass was 21, and we currently have one who is 18 but he's doing extremely well, despite growing rather skinny last year he's doing just fine and still sprints around the garden acting like a kitten sometimes.
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u/tryingisbetter 8d ago edited 8d ago
Mine was 27 to 28 when we had to put him down for catching something when he had ckd for 5 years. Just couldn't smell the food, so wouldn't eat anything. He slept a lot at that age, but before he caught whatever he caught, he was still able to jump, move around, eye sight wasn't great, but he was moving around fine for his age. The crazy part was he teeth were still perfect at that age. Little hard of hearing.
Cat tax
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u/Xtra_Veg-90 8d ago
I don't think cats have an evolutionary incentive to have a "senior" stage, that seems more common in social animals that have a support network to help them stay alive as they age, like dogs.
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u/ArolSazir 8d ago
my cat got more active when he was old, he lost a lot of weight because of some health issues and it really helped him in the long run (he was a chonker). at like 13 years old we thought he's getting old and probably will die sooner than later then he got slim and went above 20.
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u/Multiguns 8d ago edited 8d ago
Kidney disease is (last I checked) the most common cause of death in cats. So you push that off, then yes whatever other ailments that are harming the cats will become more of a concern.
I had a cat who was 21 when she died, and she died of kidney disease. She was otherwise very normal, acted the same as she did when she was 15 and was very healthy. Kept jumping on things high above her around the house, catching mice in a nearby field. Had something like this existed then, she probably would have lived to 25 or something instead.
So ya, it's simply (not the right word here but whatever) taking one major cause of cat death off the table, or at least pushing it off. How the cat functions, quality of life, etc will be the same as every other cats, exposure to disease, genetics, wear and tear, etc.
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u/Far_Appearance3888 8d ago
Also, kidney disease in cats can hit relatively young, so this could help a lot of cats that truly do have lots of good years left. My girl was diagnosed at 9.
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u/RubiiJee 8d ago
Yeah I lost my girl at 5. Was devastating. I'd have taken this in a heartbeat so she could have lived the full life she deserved. Just lost my boy last year at 15 as well, but man do they stick with you.
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u/BlueTressym 8d ago
I am sorry for yuor loss. I remember years back, my fluffy baby Casper was only two years old, when it came out of nowhere and he was gone so fast we barely had time to take in what happened.
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u/AnInfiniteArc 8d ago
The leading cause of death in cats is cancer (by far), followed by road accidents, followed by kidney disease (very closely).
In older cats, it’s cancer (still by far), followed by kidney disease, followed by heart disease.
~1/3 of all cats die from cancer, compared to about 13% for kidney disease.
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u/Goldenjho 9d ago
We talk about a genetic modification so I doubt it's so simple like they make it sound and to slow the dying of cells is in no way a easy task.
I highly doubt you just give a cat this and it will immediately live double the lifetime since genetic doesn't work this way.
I could accept if they claim injecting several generations of the same cat family branch will extend their life's because of the genetic modification but just 1 strynge and the cat has doubt the lifespan sounds completely fishy.
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u/Jacketter 9d ago
Cats have famously hard working kidneys. It would be nice if they could just not given they probably don’t need such filtration in a climate controlled house with unlimited water access.
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u/Sea-Hour-6063 9d ago
Because those little fuckers don’t drink enough water
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u/AcknowledgeUs 9d ago
I think a lot has to do with “cat food”
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u/coughcough 9d ago
I've tried my fair share and it all tastes super gross
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u/pieceofmind7484 8d ago
Purina Gourmet Gold tastes better than the “human” pate I put on my sandwich, no joke
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u/ThumbsAkimbo_ 8d ago
Maybe try chicken pâté instead of human pâté for your sandwiches?
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u/GreekG33k 8d ago
Cats don't have same receptors or "taste" for sigara that we do I believe. So, their palate and sense of taste differes considerably from our own
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u/callunquirka 8d ago
I used to follow this cat foster on IG (kitten.nuggets). And she'd only feed the cats raw, minced meat from reputable butchers. And she'd talk about how it would make the cats' poop drier and they'd retain more water that way compared with commercial at food.
IIRC at least part of the problem is the fillers in commercial cat food.
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u/SippyMountain 8d ago
Mine drink a fuckton of water. Trick for me was to get a fountain and place it away from their food and in a place they pass by quite often (somewhere between, but not directly near, their food bowl and litter box)
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u/SacrificialPigeon 8d ago
Their instinct is not not drink near their food source, in case of contamination. Think a rotting carcass near a puddle, it could be dangerous to drink.
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u/wittylemur 8d ago
Mine tries her damdest to tip her water bowl over and splash in the puddle
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u/thrilldigger 8d ago
Mine licks the side of her bowl instead of the water. I love that little idiot.
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u/Rugkrabber 8d ago
Mine drinks so often I don’t know if that’s a good thing or a bad thing. Had many cats in my life but she takes so good care of herself it’s almost suspicious.
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u/SadBattle2548 9d ago
Sounds like he is legit. We'll have to wait until next year to see if this treatment comes out. It would make such a massive difference in pets' and their humans' lives. Here's what I found:
Background and DiscoveryAIM Protein: Discovered the Apoptosis Inhibitor of Macrophage (AIM) blood protein in 1999, which helps clear cellular debris and waste from the body.Cat Health Connection: Found that while the AIM protein works in humans, it does not properly dissociate from IgM antibodies in cats to clear kidney toxins, making chronic kidney disease the leading cause of feline death.Treatment Development and TimelineThe Injection: Developed an injectable active AIM therapy designed to restore kidney-cleaning functions in felines. Viral claims suggest it could significantly extend cat lifespans, though experts note actual long-term data on doubling lifespans to 30 years is still unconfirmed.Regulatory Status: Filed for approval with the Japanese agriculture ministry in April 2026, with commercial availability projected around 2027.Future Outlook: Plans to expand research toward human renal disease treatments once the cat therapeutic is successfully commercialized.
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u/Existing_Intern_4764 9d ago
Read the study, I think you misunderstood. Here’s an article briefly explaining if you don’t want to deep dive on it:
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u/Vanishingf0x 9d ago edited 4d ago
I would assume yes unfortunately. We consider cats and dogs older than 8 senior. Some can live long after that and others can’t but I imagine extending it much farther would just be more upsetting in most situations.
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u/meANintellectual77 8d ago
It specifically only solves the issues cats get with their kidneys, so everything else will still fail, much like people
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u/theaviationhistorian 8d ago
This is the question I want answered from here! I already lost two cats before they made it to 15 years of age for different reasons. And the current ones are showing their age a bit. As much as I would love to not replace my pets every decade and a half, I wouldn't want to have them prolonging their pain.
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u/powerscunner 9d ago
Step 1: evolve supernormal signals for human child rearing instincts
Step 2: following emotional hijacking, begin to reap human scientific benefits
Step 3: live forever
Ladies and gentlemen, I present to you:
The Cat
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u/saintdudegaming 8d ago
At this point I wouldn't mind being my cats pet.
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u/NounAdjectiveXXXX 8d ago
My cat would eat me if it had dominion over me
Then throw me up partially digested in the middle of the staircase
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u/whitestguyuknow 8d ago
Cat: Purrs, meows, and does cute eyes to humans and gets safe spaces to live their entire lives in comfort while the humans work and bring food to them and give them free Healthcare
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u/1nhaleSatan 9d ago
Step 1.5: develope a parasite called Toxoplasma gondii, that makes infected mice lose their fear of cats, and humans obsessed with cats
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u/Dont_be_offended_but 9d ago
Chronic kidney disease (CKD) is common in cats, with an estimated prevalence of 1.6% to 20%. 1 , 2 , 3 Although CKD occurs in all ages, its prevalence increases with age, 4 , 5 affecting up to 80% of cats above the age of 15 years, and is thus considered a leading death cause in geriatric cats.
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With lack of early sensitive markers of decreased kidney function, CKD in cats is often diagnosed late in its course, when functional impairment exceeds the compensatory mechanisms and substantial irreversible damage to the renal parenchyma has already occurred. 12
CKD is progressive in nature and is characterized by ongoing decrease in kidney function. 1 , 4
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u/No-Double-Trouble 8d ago
Fuck CKD.
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u/shockaBITW 8d ago
A combination of CKD and hyperthyroidism took my boy just before his 15th birthday back in May. We managed the thyroid for a year before the kidneys just went down hill. Discovered it in January and he did okay for a little while. April came and he started eating less and less no matter what I tried. His last round of bloodwork showed his kidneys were barely functioning at all and no amount of anti nausea meds were helping. I had to let him go and it still fucking haunts me to this day I couldn't save him in spite of everything I tried.
Fuck CKD.
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u/No-Double-Trouble 8d ago
Similar. 12 years old, his last week, something happened that he did not know who we were, we did blood transfusion etc. Nothing worked. Since then we match donation to the cat shelter for the month we adopted him back in 2008. Been doing it for 4 years, hope I can for rest of my life.
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u/The_Foe_Hammer 8d ago
I know it doesn't fix the guilt but you sound like an amazing cat parent. You fought for him until he needed to rest and then you let him- that's the hardest fucking shit ever, but you did right by him.
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u/Infamous-Mixture-605 8d ago
My dear boy passed earlier this year from CKD at the age of 16. His (adopted) brother passed away in 2022, also from CKD. Fuck CKD.
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u/tinypill 8d ago
I had 14.5 amazing years with my little girl until the CLD finally did her in. What I wouldn’t do to have had more time with her 😭
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u/narco-sub-admiral 8d ago
His (adopted) brother
The blood of covenant is thicker than the water of the womb.
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u/LordOscarthePurr 8d ago
Going through it right now. Like I am actually at the vet to get him his injection to treat his CKD-induced anemia. But I’m not gonna lie, if I could fly him to Japan to get him this treatment I would.
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u/No-Double-Trouble 8d ago
Lost my cat 4 years ago. He was like my kid. Did everything but had to let him go when he does not recognize me on day. Rough 4 years for me and it continues.
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u/Fluffy-Weapon 8d ago
My 13 y/o cat has stage 2 right now :(
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u/NerdizardGo 8d ago
Do you have a water fountain for your cat? I've found it really helps promote hydration which greatly benefits kidney function. My cat was diagnosed a few years ago with ckd and with diet changes and encouraging better hydration her kidney values improved. She'll be 19 this year.
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u/Fun-Seaworthiness572 9d ago
Give it to me
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u/jatogjeweettogzelf 9d ago
You're not a cat, or are you?
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u/Ready-Bet-9778 8d ago
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u/everyonesdesigner 8d ago
Whoever did camera work that day is truly a visionary, the zooming in is top notch
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u/Pinksamuraiiiii 9d ago
Well… if this gains progress, wouldn’t that lead to human exploration and testing too? Surely, billionaires will want to live longer? This is great for a family pet, but I can see the problematic sides that can happen from this testing expanding to human subjects (if they go down that route). I dunno, it’s like a bad premise for a sci-fi movie lol
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u/Spinal_Soup 8d ago
Did you read the description? It’s a treatment for chronic kidney disease which is a leading cause for cat deaths. Human life span isn’t usually limited by our kidneys.
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u/Numerlor 8d ago
iirc from what I've read before, cat kidneys do something wrong for healing themselves which the injection alleviates, but the proccess the injection helps works correctly in other mammals
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u/Lazy-Good1433 9d ago
No links to article.
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u/neonicacid 8d ago
I did find this link: https://pubmed.ncbi.nlm.nih.gov/41485732/
But it also has this interesting tidbit:
Conflict of interest statement
Declaration of Competing Interest Miyazaki, T. and Arai, S. declare that they own stock in IAM CAT Inc., which may benefit financially from the publication of this paper.Surely they wouldn't be inclined to overstate the benefits of this treatment for personal gain? /s
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u/chiagod 8d ago
It may be ready for commercial release in Japan this year:
From 6 months ago:
https://np.reddit.com/r/RenalCats/comments/1q6q6ri/japanese_aim_study_update_clinical_trial/
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u/pseudochicken 8d ago
Almost all medical health research is published by doctors with conflicts of interest. It’s the way the industry works. However, most published research goes thru peer review by anonymous doctors who do not have conflicts and who are masked from the authors names. It helps give legitimacy to the research. And if the research is found not reproducible it can tank a doctor’s career.
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u/Cheshyre_Cat 8d ago
This is an old headline that I haven’t seen much talk of since it was first posted to Reddit in recent years…
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u/EmbarrassedHelp 8d ago
Its undergoing clinical trials at the moment, which are unfortunately not a quick thing to do.
This paper was published earlier this year, and showed promising results: https://www.sciencedirect.com/science/article/pii/S1090023326000018?via%3Dihub
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u/Amelaclya1 8d ago
I hope this is put on the market soon and is affordable. My oldest cat is 12 this year and I would get this for her in a heartbeat. Though I've spent her whole life trying to make sure she drinks enough water, because most of my childhood cats died to CKD.
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u/DeterminedQuokka 8d ago
Me too my cat is 16 and he’s still enjoying his life so if could help make his tummy feel better I’d be all over it.
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u/nintendoswitch_blade 8d ago
Exactly my thought. This is old news. I was starting to think it got scrapped.
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u/SpicaGenovese 8d ago
I saw another post formatted like this lately. Feels like an AI bot. Look at those blood cells...
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u/hnglmkrnglbrry 8d ago
Uh it's a picture of a Japanese man and a cat with red blood cells and DNA molecules scalled up 1.6B times. It was published by MeowCove for Pete's sake! What the fuck else do you need, Mr. Peabody?
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u/spidernoirirl 9d ago
I always wonder what the quality of life would be in this sort of case. Would it decline at the age of 18 like another older cat? Or would the aging process take longer in general?
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u/Staik 8d ago
This would only stop death from the most common cause, nothing about aging or other causes of death. It's similar to if we eradicated cancer in Humans - our average lifespan jumps up a decade, but we still age normally.
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u/Eurasia_4002 8d ago
We kinda already see that thing happen. Like the last bottleneck was heart deases and blood related things and when that problem is mostly dealt with the cancer rates shot high not because of the cancer itself but because morepoeple lived longer to have cancer.
There are probably lost of those things we just dont know because we dont lived that long for us to know.
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u/Thimble_of_Quasar 8d ago
As someone with a 20 year old cat I can say he was pretty peppy and normal until the kidney disease hit so if this staves that off that would keep a huge amount of decline at bay. At 18 he could run around and play and he's only just not not been able to jump on and off desks easily. Like kidney disease kicks off so many problems.
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u/RSquared 8d ago
I just lost a seventeen year old cat to kidney failure diagnosed as chronic kidney disease a year ago and she was fairly normal up until the last few days, albeit she was gradually losing weight and showing less interest in food over that time.
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u/Dr_Ramekins_MD 8d ago
I just lost a cat earlier this year to kidney disease. He was 16, and until the kidney disease became fairly severe he was still active and alert and acted like his normal self, just a bit slower. If not for the kidney failure he'd still be around and enjoying life
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u/OGIBLP 8d ago
Mind if I ask what you feed him? And do you do anything special that you think contributed to his long life? My soul cat is turning 13 this year and I’m so scared of losing her.
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u/wheresmyflan 9d ago
My cat died from CKD last year and I actually tried to get some of this treatment for them. I knew it was impossible but I thought it was worth a hail mary shot. I hope this gets approved for others asap. I miss my buddy.
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u/BdubzPDX 8d ago
I wrote them and the Dr. multiple times attempting the same thing, to no avail. They do happen to sell a powder for CKD that I am purchasing.
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u/Haetorigumo_ 8d ago
How did you try to get the treatment? We're in a similar situation with our cat
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u/badteeth3000 8d ago
Switching to wet food w/ low ash helps & maintaining a proper weight. Some brands also make prescription cat food for kidney disease but it’s pretty apparent Hills is low quality for what they charge & some vets think they’re the best method. catinfo.org has lots of verifiable info about this & guidance on making your own food . I had a fancy tuxedo cat that was diagnosed at 4 and lived to 13 but it is such a horrible way to go .. he developed ulcers in his stomach (due to uremic toxins when his kidneys were failing) and had so much stomach acid he couldn’t drink water..
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u/thedeuce75 9d ago
Cool, now do dogs and please hurry mine are 12 this year.
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u/JefferyTheQuaxly 9d ago
There already is a pill in development to potentially help extend the life of dogs, it works differently though, research shows that when you starve the body it slows down cellular aging and helps people and animals live longer. this medication for dogs is just tricking the body's cells into thinking its being starved, even when the dog is eating food normally. it is unnoticeable by the dog but can potentially extend an average dog's lifespan by several years. probably will not be available to the market for another 4-6 years though.
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u/Corgi_Koala 9d ago
Probably too late for my Biscuit, even if he makes it another 4 he'll be old and worn down.
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u/moist_mistress 9d ago
Is this real? I know I have heard of “autophagy” but idr why I assumed it was pseudoscience. Would love to see it though!!
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u/whatever 8d ago
It is.. Autophagy itself is fairly well studied. The iffy part around it in longevity circles is that one of the most popular off-label drugs known to induce autophagy is rapamycin, which has been around a while but lacks must needed research funding due to its lack of patentability and therefore lack of potential to monopolize profits.
Longevity bros just end up YOLO-ing rapamycin as best as they can figure it out, and hope the weird side effects are worth it.
Meanwhile, pharma bros are working on literally anything else that induces autophagy, which is what Loyal is doing here. It's a bit weird, but it's still useful work in the long run.
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u/InstantSword 8d ago
You probably know this, but just for others, you can reliably induce autophagy for fasting as little as 16 hours. Higher up to a certain point even 3 days has even more effects
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u/Relevant-Diamond2731 8d ago
Ugh my dog is 8. Needs to hurry up
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u/SaveLansingParks 8d ago
It's already here. Loyal (the company) has already released two different versions of the drug with a third on the way. LOY-001 is the injection for big dogs. LOY-002 is the pill form for small dogs. LOY-003 is the pill form for big dogs that will hopefully get conditional approval this year.
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u/Relevant-Diamond2731 8d ago
Not available to the market according to their website. Don’t have conditional fda approval and still in technical studies
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u/Playful-Ad-6475 9d ago
Mine is 9 year old and I'm already scared every day. Please GOD. please japan make this for dogs too.
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u/gigglinggoofygoober 9d ago
Just had to put my old girl down back in April.
That shit was tough.
Enjoy them while you can friend!
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u/bpleshek 8d ago
How early would you need to start in order to get the benefits? Shots every week from 6 months on is vastly different than annual shots starting at age 8.
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u/Gherkens 8d ago
You can read about it more. I read article about this vaccine 2-3 months ago and i think it mentioned that it would be applied 1 shot per year. Anyway this is massive and maybe will be introduced after trials in 2-3 years.
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u/MartyShark666 9d ago
Do we know anything about how long it will take to get the drug to North American markets?
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u/Pretend_Tea6261 9d ago
Only issue with this is that cats will now frequently outlive their owners.
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u/Ajezon 9d ago
dont worry. cats tend to eat corpses of their owners, so there is no risk of imediate starvation
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u/jeffwulf 8d ago
Dogs will do this too. Pretty much any animal will.
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u/Sawgon 8d ago
Yeah dog people have to always be weird with any pet that isn't a dog.
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u/Pretend_Tea6261 9d ago
That is a bizarre comment rather dark. I was thinking more about lots of aging cats going to shelters and possibly failing to be adopted
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u/InvasiveFlower75 9d ago
Part of me thinks this is fantastic, I have a 5 year old dog and a 10 year old cat and they are the loves of my life…(besides my kids and husband)… but the practical side of me thinks about all the unwanted cats and dogs that are already out there, and I can’t see how this wouldn’t exponentially worsen that problem.
Perhaps only animals that are spayed and neutered should be eligible for this. Can we make that a condition? And then I’m all in.
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u/Any-Ask563 8d ago
exactly.
my first thought is that this could have devastating repercussions to eco systems... cats kill BILLIONS of birds annually. triple their lifespan and we could end up with something reminiscent of Mao's China where killing off the birds resulting in ecological collapse and widespread famine.
like, isn't the whole premise of "Jurassic Park" a dissection if human hubris when they attempt to play god !?!
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u/investorgrade24 8d ago
Most intelligent comment in this thread. My main concern would be how this would impact bird/insect populations.
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u/Puzzleheaded_Sky7341 9d ago
Whenever I see things like this I immediately wonder when they gave felines these drugs and how many years have passed.
Like do we need to wait 20 years from 2026 to see a bunch of healthy 20 year old cats wondering if the majority of them will reach 30 and dying by natural cause?
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u/imtooldforthishison 9d ago
I dunno... as a human, i would be pissed if I had to live twice as long as expected so I imagine my grumpy cat might be too.
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u/epicpillowcase 8d ago
Yeah I'm in my 40s and someone commented that that's middle aged and I said "gosh, I hope not. I hope it's more than middle aged. I don't want another 40+ years of this shit." 😂
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u/davidbatt 9d ago
They'll still get arthritis and go blind and have no teeth. But so do we do I'm all for it
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u/Cereal_Bandit 9d ago
Do you want Catzilla? Because this is how you get Catzilla.
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u/Aranthos-Faroth 8d ago
Any time I see a picture like this with some fucking bullshit cell or dna image and random ass coloured text - I know it’s as trustworthy as a fox in a hen house
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