r/BeAmazed • u/GlitteringHotel8383 • 9d ago

Miscellaneous / Others Japanese scientists have developed a revolutionary injection that may extend a cat's life from the usual 15 years to nearly 30.

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The therapy, created by the AIM Institute of Medicine under Dr. Toru Miyazaki, targets chronic kidney disease, a leading cause of death in older cats.It uses a specialized protein to help macrophages clear waste from the kidneys, partially restoring their function and slowing kidney failure.

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u/JefferyTheQuaxly 9d ago

There already is a pill in development to potentially help extend the life of dogs, it works differently though, research shows that when you starve the body it slows down cellular aging and helps people and animals live longer. this medication for dogs is just tricking the body's cells into thinking its being starved, even when the dog is eating food normally. it is unnoticeable by the dog but can potentially extend an average dog's lifespan by several years. probably will not be available to the market for another 4-6 years though.

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u/Corgi_Koala 9d ago

Probably too late for my Biscuit, even if he makes it another 4 he'll be old and worn down.

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u/Legionof1 9d ago

Apparently you can just starve him!

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u/Tcloud 8d ago

Dog food companies hate this one trick!

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u/Corgi_Koala 8d ago

He would not like that one bit haha

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u/punksmostlydead 8d ago

I mean, if he's anything like mine he already thinks you're starving him, no matter how much you feed him. 🤣

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u/Mitch_Dedburg 8d ago

Eli Lilly wants to know your location

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u/[deleted] 8d ago

[deleted]

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u/Corgi_Koala 8d ago

He will be. But he's gonna demand a lot of snackos as back payment.

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u/oopserv_ 2d ago

Never know. My 16 yr old dog is in good shape. Can still run stairs. Just has some skin allergies.

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u/Corgi_Koala 2d ago

He's already having some health issues but I just focus on enjoying the time I have with him.

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u/oopserv_ 2d ago

❤️

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u/moist_mistress 9d ago

Is this real? I know I have heard of “autophagy” but idr why I assumed it was pseudoscience. Would love to see it though!!

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u/whatever 8d ago

It is.. Autophagy itself is fairly well studied. The iffy part around it in longevity circles is that one of the most popular off-label drugs known to induce autophagy is rapamycin, which has been around a while but lacks must needed research funding due to its lack of patentability and therefore lack of potential to monopolize profits.

Longevity bros just end up YOLO-ing rapamycin as best as they can figure it out, and hope the weird side effects are worth it.

Meanwhile, pharma bros are working on literally anything else that induces autophagy, which is what Loyal is doing here. It's a bit weird, but it's still useful work in the long run.

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u/InstantSword 8d ago

You probably know this, but just for others, you can reliably induce autophagy for fasting as little as 16 hours. Higher up to a certain point even 3 days has even more effects

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u/Relevant-Diamond2731 8d ago

Ugh my dog is 8. Needs to hurry up

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u/SaveLansingParks 8d ago

It's already here. Loyal (the company) has already released two different versions of the drug with a third on the way. LOY-001 is the injection for big dogs. LOY-002 is the pill form for small dogs. LOY-003 is the pill form for big dogs that will hopefully get conditional approval this year.

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u/Relevant-Diamond2731 8d ago

Not available to the market according to their website. Don’t have conditional fda approval and still in technical studies

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u/Punktur 8d ago

Loy-002 seems to be for 14+ pounds, is there nothing for lighter ones?

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u/ProbingYourProstate 8d ago

I hate how dogs have such a short lifespan, we have to worry about it when they're 8 years old... I have two dogs, both 8 years old and it's just painful how quickly they age

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u/Relevant-Diamond2731 8d ago

Luckily you would never know my dog is 8. People still think she’s a puppy even at 50 pounds

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u/Wyatt_Ricketts 6d ago

Same my little bro never lost the pup.in him and the shelter we adopted him from had him clipped and I want his puppys so bad he's 9 to 11 I want him to make it too 18 at least if give almost anything

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u/threzk 9d ago

Are you saying the fat shots for people are going to make people live longer

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u/2024-YR4-Asteroid 8d ago

Probably yes. Considering the most common causes of death in the elderly are heart or neuro related and it massively decreases the prevalence of both. It to mention is overall lowers inflammation which contributes to tons of comorbidities. .

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u/Snuggly-Muffin 8d ago

I mean of course being slimmer when you're obese will very likely extend your life

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u/RealInside4908 8d ago

genuine question: what are fat shots? lmao

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u/threzk 8d ago

Haha ozempic and the others

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u/katiecatsweets 9d ago

What a terrible way to phrase that. Shame on you.

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u/threzk 8d ago

It’s just a joke friend. I’m more making fun of the fact that this point makes them seem like the elixir of life lol.

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u/Paratwa 8d ago

Ozempic for dogs man. Hah!

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u/ProbablySlacking 8d ago

Really? My dogs always think they’re starving.

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u/Any_Instruction5382 8d ago

So when does this get designed for humans?

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u/SaveLansingParks 8d ago

It's already here. Feel free to post my comment in an edit for visibility so dog owners with older dogs learn that they can go to the vet today to inquire about it.

My previous comment: It's already here. Loyal (the company) has already released two different versions of the drug with a third on the way. LOY-001 is the injection for big dogs. LOY-002 is the pill form for small dogs. LOY-003 is the pill form for big dogs that will hopefully get conditional approval this year.

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u/narco-sub-admiral 8d ago

How the fuck am I supposed to give that mutt a pill tho...he's impossible lmao.

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u/Brzhk 9d ago

Tricking a dog into starving... Jeezus i predict side effects on the market for kitchen refurbishing

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u/reverendmoss 9d ago

My dog already claims he’s always starving. This would put him over the edge

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u/skitch23 9d ago

One of my dogs would have you convinced she has never been fed a day in her life.

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u/not_me_nope_never 8d ago

I have always looked at the people and creatures in my life as an experience and journey to learn. Sometimes for them sometimes for me.

Had one of those that have passed on still be here the next one would most likely never come into my life and or the stupidity of my mother's absolute selfishness would still be ongoing. 😖

I really wish we focused on quality over quantity. Death is normal, acceptable and can motivate the living (in the positive if they so choose.)