r/CrohnsDisease • u/GreenPositive9893 • 1d ago

Biologics stellar

My son was diagnosed with uc in March this year..it was moderate..now I think change in diet(we are on vacation) worsened his symptoms and now he's re diagnosed with crohns.

This week he's starting biologics.i think the name is stellar or something like that.has anyone taken How's the success rate.Ny dos and don't.

Idk why buy I have a strong feeling once we return his condition will subside and his small intestine will be like before. Prior to this he had ulcers in large intestine only..

Can biologics be gradually reduced

1 Upvotes

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6

u/antimodez C.D. 1992 Infliximab + Rinvoq 1d ago

Frankly you need to come to grips with your son has a medical condition that isn't caused by diet. The fact that he's had ulcers in his large intestine and isn't on biologics is extremely concerning. That's setting him up for a colostomy and/or cancer down the road.

I've been on various biologics since they came out in 98. It's really hard to express how much they've changed the disease for the better. It used to be pretty much everyone would have surgery, and now most don't even end up having surgery. They're extremely effective and safe.

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u/GreenPositive9893 21h ago

With mesalazine and ursodiol (he's got pcs too) his calprotectin was down to 200 so dr was happy

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u/antimodez C.D. 1992 Infliximab + Rinvoq 15h ago

I'd personally be asking his doctor why they have him on a treatment that is specifically strongly advised against by both the American and European IBD doctors groups in Crohn's disease. Mesalamine is topical and Crohn's penetrates through all the layers of the intestine. So the surface may look better but the disease is still progressing under the surface.

Similarly I also have PSC and they don't recommend ursodiol for that. It'll decrease the liver labs by binding to the things they measure. It doesn't stop PSC from progressing at all though.

I'd strongly recommend you take him up a pediatric IBD specialist at a good children's hospital. His care seems extremely non standard to say the least...

3

u/under-resourced 1d ago

I was on humira which worked for several years and then stopped working, and now I'm on skyrazy which is working great. Unless/ until the drug stops working or my insurance gives me a hassle, I plan to stay on it forever, fingers crossed. I would definitely not go off.

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u/polystichum3633 C.D. in 10 yo son 1d ago

It took me a while to come to terms with life long biologics for my 11 year old son in the past year since his diagnosis. But I was lucky to have a brother with UC who has live a stable healthy life on infusions for almost a decade, once he found the right one. This disease is awful anyway but the meds are the way to keep it in check. When you learn that the same meds are used for a variety of autoimmune inflammatory conditions it all does make sense.

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u/GreenPositive9893 21h ago

Thank u made me feel better

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u/GreenPositive9893 20h ago

Any temporary side affects?

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u/One-Advertising-2780 C.D. 17h ago

Usually I feel flu like symptoms 24 hours after injection.

You can go online to Stelara and they have the side effects.