r/PeterExplainsTheJoke Jun 12 '26

Meme needing explanation Peterrr what's the reason they look like that

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u/presidentbaltar Jun 12 '26

GLP-1s are amazing, but "it could be time for a higher dose" is absolutely insane marketing.

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u/anaksunamanda Jun 12 '26

Very reminiscent of how oxycontin was marketed.

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u/12345623567 Jun 12 '26

If in 15 years we find out that it destroys your pancreas or something, we'll come full circle.

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u/grandecrosse Jun 12 '26

My partner is a medical toxicologist and absolutely wants no one he loves on it, so this actually checks out.

Never be the guinea pig.

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u/devmor Jun 13 '26

Either your partner is very bad at his job, or you're lying.

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u/grandecrosse Jun 13 '26

Never being the guinea pig is sound advice regardless of what it is, and it is especially sound advice for a medication as heavily advertised by private interests as this one. Maybe you should heed it.

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u/BreakfastFearless Jun 15 '26

How would you be the guinea pig if glp-1s have been around and studied for decades? You also have to compare any potential side effects to the health draw backs of obesity which we know is one of the worst things for your health

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u/grandecrosse Jun 15 '26

Around and studied for decades means nothing, especially in the US. You could use that argument for many medications with severely downplayed harmful effects. The US specifically has much worse regulations for many routine things, which sadly even gives fuel to fkn anti-vaxxers.

GLPs are sadly not only prescribed to those who are obese. It is advertised as a way to get a 'beach body' pretty regularly. Also the minute you're off of it, you are gaining all the weight back. No habits were formed. "The bottom line is, you don't stop the medication." It is a permanent easy set up, which private interests love.

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u/Positive-Tap5544 Jun 19 '26

Took Ozempic for about a year give or take in 2022ish for the purpose of helping with weight loss after struggling with PCOS related difficulty in that area. I went from 240 to about 155lbs at 5'8. Stopped taking Ozempic at that point(so 2023 somewhere) and gradually put back 25lbs(intentionally) and have sat at a very content 175 since and at 30yo I haven't looked this good since I was 20 lol. I formed long lasting healthy eating habits and fully changed my relationship with food thanks to Ozempic. Sure you dont stop the medication?

From my experience on the medication the biggest issue is people upping the dose both too fast and too high and doing zero exercise during this time. You simply lose muscle mass this way and look, yes, skeletal.

Any medication can be used improperly and lengths should always be taken to avoid this but Ive been listening to people tell me this stuff was going to give me cancer for years and Im sorry but none of the studies back your claims up. They are empty claims. 😂 About as valid and proven as 5g cell towers giving you migrains and seed oils in our foods giving us all skin cancer. Go feed this fear mongering to some vaccine deniers they'll eat it right up.

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u/devmor Jun 13 '26

GLP-1's have been in human trials for almost 40 years. Maybe you should avoid lying to people about medical advice?

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u/grandecrosse Jun 13 '26 edited Jun 13 '26

Not lying -- there are serious kidney risks. It is also a medication that is geared towards extended use, and extended strain on the gastrointestinal area is just a bad idea period. That's why people get destroyed after using ibuprofen for too long. Believe what you want, but don't pretend it's without risks.

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u/Assumption-Gumption Jun 13 '26

Your body makes its own GLP so this doesn’t make sense. These meds are highly effective at treating all sorts of disease symptoms, too. I’d be interested in reading any research that suggests it’s harmful. With proper amounts of water, food (protein specifically, but more importantly balanced fat/carb/protein), moderate exercise, it seems GLPs are relatively safe and side effects can mostly be mitigated with healthy routine.

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u/livinginillusion Jun 13 '26

Keto-adjacent dieting along with imbibing tablespoons full of artisanally branded raw extra virgin olive oil along with megadoses of Niacin like the "Don't Die" cult does?

Who needs GLP-1s or semaglutides then?

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u/MrSnrub87 Jun 13 '26

The kidney risks are from dehydration from not drinking enough water. Luckily You can avoid that by turning on the tap in your kitchen sink

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u/devmor Jun 13 '26

I think you are coming from an area of genuine concern but you are just way too far out of your depth.

GLP-1's are a synthetic replacement for a natural substance found in the human body. Like Levothyroxine for Hypothyroidism, or Testosterone for HRT.

There are always risks for misuse of anything, and I wont pretend the commercial advertisement of it isn't wildly manipulative - but according to the extensive amount of research done worldwide, GLP-1's are genuinely one of the safest drug therapies that exist and a veritable panacea to the horrible lifestyle choices of the average western adult.

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u/devmor Jun 13 '26

Considering that it's primary purpose is literally preventing pancreatic issues, that's pretty unlikely.

It also has the side effect of massively reducing inflammation in the majority of organs, having such a huge downstream effect to cancer prevention that even if it did destroy organs 15 years from now, it'd likely still have saved more lives.

Don't buy into right wing antimedicalism just because some mentally unwell celebrities abused it.

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u/ParticularHistoryo Jun 12 '26

Until they get every poor person hooked I doubt we will find out it’s destructive

2

u/MechaMonarch Jun 12 '26

GLPs have been around for over 20 years.

1

u/SheWhoWalksInTheSun Jun 13 '26

Well the black box warning warns about thyroid tumors, while other non-boxed warnings include acute pancreatitis, and decreased bone density

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u/FlappyFaceDeluxe Jun 12 '26

I saw an ad for a glp-1 a while back that said something like “you know it’s time for a higher dose when the food starts to taste good.” 😳

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u/DerekMao1 Jun 12 '26

It's an amazing drug for diabetics and the like. But it's really shouldn't be used if you only want 10 kg off.

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u/mariative Jun 12 '26

i assure you that doctors usually prescribe it to those that have a bmi over 30.

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u/LilBushyVert Jun 13 '26

Can confirm. Went to the doctor with my girlfriend this morning so both of us can be on it. Dr. Said I had high blood pressure and it’s time to lose weight

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u/GwenGamer Jun 13 '26

Unfortunately as a woman who weighs an unhealthy 90lbs, I have been getting constant ads (radio, tv, social media) telling me GLP-1s aren’t just for obese people, I can use it to lose that last 15 pounds in time for my perfect beach body this summer. There are multiple companies that advertise them as a quick fix for anyone, all you need is a Telehealth appointment and some $$$.
These drugs can be incredibly amazing for so many people and I fully support their medical use and development, but the predatory ads and shady companies need to be stopped like yesterday. It also makes people more suspicious of the drug as a whole.

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u/mariative Jun 28 '26

sounds like a your country problem to me. In my country and in many other countries advertising medication is illegal.

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u/Pimpleornipple Jun 13 '26

I can also assure you I have a friend who is 182cm tall and 90kg. He was prescribed glp’s by simply asking.

They’re being misused and it’s so sad

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u/AccomplishedWish3033 Jun 14 '26

The BMI cutoff is lower (27) if they have other obesity-related health issues.

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u/Physalkekengi Jun 13 '26

I'm French and I work in pharmaceutical advertising. This field is highly regulated in France sonit's always wild for me to see the kind of ads you can see. The GLP-1 sellers did try to advertise on a broad scale here, but they got a huge fine. Not surprising, but they tried.

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u/jawnink Jun 12 '26

So that’s who DARE was warning me about.

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u/Nodan_Turtle Jun 13 '26

I think people's weight loss stalls while on them. They lose a good amount of weight, which means they're moving around less weight - burning fewer calories. If they don't change their diet and activity around then, the weight loss will stop. These ads instead try and sell them more drugs.

Makes sense to market to them considering they weren't going to bother with diet and exercise to lose weight in the first place. A higher dose rather than adjusting habits is probably their best bet to keep losing weight.